PCL 2 (Wigger's diagram)

• a standard diagram used in cardiac physiology
• x-axis: time
• y-axis: blood pressure (aortic pressure, ventricular pressure, atrial pressure), vetricular volume, ECG, arterial flow (optional), heart sounds (optional)
• purpose of displaying all in one - illustrate relationship between values in cardiac cycle
• During isovolumetric/isovolumic contraction and relaxation, all valves are closed

	Phase	ECG	Heart sounds	Aortic valve	Mitral valve
A	Atrial systole	P	S4	Closed	Open
B	Ventricular systole – Isovolumetric/isovolumic contraction	QRS	S1	Closed	Closed
C1	Ventricular systole – Ejection 1	-	-	Open	Closed
C2	Ventricular systole – Ejection 2	T	-	Open	Closed
D	Ventricular diastole – Isovolumetric/isovolumic contraction	-	S2	Closed	Closed
E1	Ventricular diastole – Ventricular filling 1	-	S3	Closed	Open
E2	Ventricular diastole – Ventricular filling 2	-	-	Closed	Open

http://library.med.utah.edu/kw/pharm/hyper_heart1.html